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microarray dataset gse138614  (Biotechnology Information)

 
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    Structured Review

    Biotechnology Information microarray dataset gse138614
    TRIM21 is elevated in astrocytes across MS. A Analysis of TRIM21 mRNA expression in the control and white matter lesion tissues of MS patients based on gene expression profiling microarray data ( <t>GSE138614</t> ). B TRIM21 mRNA levels in PBMC samples of healthy controls (n = 12) and MS patients (n = 20) were quantified by RT-qPCR. C Representative immunoblots and corresponding quantification of TRIM21 protein levels in brain tissues from EAE mice at 28 dpi (n = 5). D Representative immunoblot images and the corresponding quantitative analysis of TRIM21 protein expression in spinal cord tissues from EAE mice at 28 dpi (n = 5). E Immunofluorescence co-localization analysis of TRIM21 (red) and the astrocyte marker GFAP (green) in brain and spinal cord sections from control and EAE mice at 28 dpi (n = 5). Scale bar, 50 µm
    Microarray Dataset Gse138614, supplied by Biotechnology Information, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/microarray dataset gse138614/product/Biotechnology Information
    Average 86 stars, based on 1 article reviews
    microarray dataset gse138614 - by Bioz Stars, 2026-06
    86/100 stars

    Images

    1) Product Images from "TRIM21 promotes astrocyte-mediated neuroinflammation in experimental autoimmune encephalomyelitis by stabilizing RGMa via K33-linked ubiquitination"

    Article Title: TRIM21 promotes astrocyte-mediated neuroinflammation in experimental autoimmune encephalomyelitis by stabilizing RGMa via K33-linked ubiquitination

    Journal: Journal of Neuroinflammation

    doi: 10.1186/s12974-026-03769-4

    TRIM21 is elevated in astrocytes across MS. A Analysis of TRIM21 mRNA expression in the control and white matter lesion tissues of MS patients based on gene expression profiling microarray data ( GSE138614 ). B TRIM21 mRNA levels in PBMC samples of healthy controls (n = 12) and MS patients (n = 20) were quantified by RT-qPCR. C Representative immunoblots and corresponding quantification of TRIM21 protein levels in brain tissues from EAE mice at 28 dpi (n = 5). D Representative immunoblot images and the corresponding quantitative analysis of TRIM21 protein expression in spinal cord tissues from EAE mice at 28 dpi (n = 5). E Immunofluorescence co-localization analysis of TRIM21 (red) and the astrocyte marker GFAP (green) in brain and spinal cord sections from control and EAE mice at 28 dpi (n = 5). Scale bar, 50 µm
    Figure Legend Snippet: TRIM21 is elevated in astrocytes across MS. A Analysis of TRIM21 mRNA expression in the control and white matter lesion tissues of MS patients based on gene expression profiling microarray data ( GSE138614 ). B TRIM21 mRNA levels in PBMC samples of healthy controls (n = 12) and MS patients (n = 20) were quantified by RT-qPCR. C Representative immunoblots and corresponding quantification of TRIM21 protein levels in brain tissues from EAE mice at 28 dpi (n = 5). D Representative immunoblot images and the corresponding quantitative analysis of TRIM21 protein expression in spinal cord tissues from EAE mice at 28 dpi (n = 5). E Immunofluorescence co-localization analysis of TRIM21 (red) and the astrocyte marker GFAP (green) in brain and spinal cord sections from control and EAE mice at 28 dpi (n = 5). Scale bar, 50 µm

    Techniques Used: Expressing, Control, Gene Expression, Microarray, Quantitative RT-PCR, Western Blot, Immunofluorescence, Marker



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    microarray dataset gse138614  (Biotechnology Information)
    86
    Biotechnology Information microarray dataset gse138614
    TRIM21 is elevated in astrocytes across MS. A Analysis of TRIM21 mRNA expression in the control and white matter lesion tissues of MS patients based on gene expression profiling microarray data ( <t>GSE138614</t> ). B TRIM21 mRNA levels in PBMC samples of healthy controls (n = 12) and MS patients (n = 20) were quantified by RT-qPCR. C Representative immunoblots and corresponding quantification of TRIM21 protein levels in brain tissues from EAE mice at 28 dpi (n = 5). D Representative immunoblot images and the corresponding quantitative analysis of TRIM21 protein expression in spinal cord tissues from EAE mice at 28 dpi (n = 5). E Immunofluorescence co-localization analysis of TRIM21 (red) and the astrocyte marker GFAP (green) in brain and spinal cord sections from control and EAE mice at 28 dpi (n = 5). Scale bar, 50 µm
    Microarray Dataset Gse138614, supplied by Biotechnology Information, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/microarray dataset gse138614/product/Biotechnology Information
    Average 86 stars, based on 1 article reviews
    microarray dataset gse138614 - by Bioz Stars, 2026-06
    86/100 stars
    		  Buy from Supplier

    Image Search Results


    TRIM21 is elevated in astrocytes across MS. A Analysis of TRIM21 mRNA expression in the control and white matter lesion tissues of MS patients based on gene expression profiling microarray data ( GSE138614 ). B TRIM21 mRNA levels in PBMC samples of healthy controls (n = 12) and MS patients (n = 20) were quantified by RT-qPCR. C Representative immunoblots and corresponding quantification of TRIM21 protein levels in brain tissues from EAE mice at 28 dpi (n = 5). D Representative immunoblot images and the corresponding quantitative analysis of TRIM21 protein expression in spinal cord tissues from EAE mice at 28 dpi (n = 5). E Immunofluorescence co-localization analysis of TRIM21 (red) and the astrocyte marker GFAP (green) in brain and spinal cord sections from control and EAE mice at 28 dpi (n = 5). Scale bar, 50 µm

    Journal: Journal of Neuroinflammation

    Article Title: TRIM21 promotes astrocyte-mediated neuroinflammation in experimental autoimmune encephalomyelitis by stabilizing RGMa via K33-linked ubiquitination

    doi: 10.1186/s12974-026-03769-4

    Figure Lengend Snippet: TRIM21 is elevated in astrocytes across MS. A Analysis of TRIM21 mRNA expression in the control and white matter lesion tissues of MS patients based on gene expression profiling microarray data ( GSE138614 ). B TRIM21 mRNA levels in PBMC samples of healthy controls (n = 12) and MS patients (n = 20) were quantified by RT-qPCR. C Representative immunoblots and corresponding quantification of TRIM21 protein levels in brain tissues from EAE mice at 28 dpi (n = 5). D Representative immunoblot images and the corresponding quantitative analysis of TRIM21 protein expression in spinal cord tissues from EAE mice at 28 dpi (n = 5). E Immunofluorescence co-localization analysis of TRIM21 (red) and the astrocyte marker GFAP (green) in brain and spinal cord sections from control and EAE mice at 28 dpi (n = 5). Scale bar, 50 µm

    Article Snippet: The microarray dataset GSE138614 was retrieved from the Gene Expression Omnibus (GEO) repository of the National Center for Biotechnology Information ( https://www.ncbi.nlm.nih.gov/geo/ ).

    Techniques: Expressing, Control, Gene Expression, Microarray, Quantitative RT-PCR, Western Blot, Immunofluorescence, Marker